America Ferrera ... Betty Suarez (16 episodes, 2006-2007)
Eric Mabius ... Daniel Meade (16 episodes, 2006-2007)
Alan Dale ... Bradford Meade (16 episodes, 2006-2007)
Tony Plana ... Ignacio Suarez (16 episodes, 2006-2007)
Ana Ortiz ... Hilda Suarez (16 episodes, 2006-2007)
Ashley Jensen ... Christina McKinney (16 episodes, 2006-2007)
Becki Newton ... Amanda / ... (16 episodes, 2006-2007)
Mark Indelicato ... Justin Suarez (16 episodes, 2006-2007)
Vanessa Williams ... Wilhelmina Slater / ... (16 episodes, 2006-2007)
Michael Urie ... Marc St. James (16 episodes, 2006-2007)
Kevin Sussman ... Walter (13 episodes, 2006-2007)
Elizabeth Payne ... The Masked Woman (11 episodes, 2006-2007)
Stelio Savante ... Steve (9 episodes, 2006-2007)
Salma Hayek ... Sofia Reyes / ... (7 episodes, 2006-2007)
Christopher Gorham ... Henry (6 episodes, 2006-2007)
Kevin Alejandro ... Santos (5 episodes, 2006-2007)
Judith Light ... Claire Meade (5 episodes, 2006-2007)
Ava Gaudet ... Gina Gambarro (4 episodes, 2006)
Rebecca Romijn ... Alexis Meade / ... (4 episodes, 2007)
Brett Cullen ... Ted LeBeau (3 episodes, 2006-2007)
Jill Latiano ... Assistant #1 / ... (3 episodes, 2006-2007)
Jowharah Jones ... Nico Slater (3 episodes, 2006)
Diane Cary ... Bradford's Assistant (3 episodes, 2006)
Lucy Davis ... Fashion TV Anchor (2 episodes, 2006-2007)
Bailey Chase ... Becks (2 episodes, 2007)
Teddy Sears ... Hunter (2 episodes, 2006-2007)
Gina Gershon ... Fabia (2 episodes, 2006-2007)
Tim Gunn ... Himself / ... (2 episodes, 2007)
Octavia Spencer ... Constance Grady (2 episodes, 2007)
Cicily Daniels ... Zelda (2 episodes, 2006)
Sal Landi ... Mr. Green (2 episodes, 2006)
Michael Edward Rose ... Edgar (2 episodes, 2006)
Rhys Coiro ... Vincent Bianchi (2 episodes, 2006)
Debi Mazar ... Leah Feldman / ... (2 episodes, 2006)
Eric Mabius ... Daniel Meade (16 episodes, 2006-2007)
Alan Dale ... Bradford Meade (16 episodes, 2006-2007)
Tony Plana ... Ignacio Suarez (16 episodes, 2006-2007)
Ana Ortiz ... Hilda Suarez (16 episodes, 2006-2007)
Ashley Jensen ... Christina McKinney (16 episodes, 2006-2007)
Becki Newton ... Amanda / ... (16 episodes, 2006-2007)
Mark Indelicato ... Justin Suarez (16 episodes, 2006-2007)
Vanessa Williams ... Wilhelmina Slater / ... (16 episodes, 2006-2007)
Michael Urie ... Marc St. James (16 episodes, 2006-2007)
Kevin Sussman ... Walter (13 episodes, 2006-2007)
Elizabeth Payne ... The Masked Woman (11 episodes, 2006-2007)
Stelio Savante ... Steve (9 episodes, 2006-2007)
Salma Hayek ... Sofia Reyes / ... (7 episodes, 2006-2007)
Christopher Gorham ... Henry (6 episodes, 2006-2007)
Kevin Alejandro ... Santos (5 episodes, 2006-2007)
Judith Light ... Claire Meade (5 episodes, 2006-2007)
Ava Gaudet ... Gina Gambarro (4 episodes, 2006)
Rebecca Romijn ... Alexis Meade / ... (4 episodes, 2007)
Brett Cullen ... Ted LeBeau (3 episodes, 2006-2007)
Jill Latiano ... Assistant #1 / ... (3 episodes, 2006-2007)
Jowharah Jones ... Nico Slater (3 episodes, 2006)
Diane Cary ... Bradford's Assistant (3 episodes, 2006)
Lucy Davis ... Fashion TV Anchor (2 episodes, 2006-2007)
Bailey Chase ... Becks (2 episodes, 2007)
Teddy Sears ... Hunter (2 episodes, 2006-2007)
Gina Gershon ... Fabia (2 episodes, 2006-2007)
Tim Gunn ... Himself / ... (2 episodes, 2007)
Octavia Spencer ... Constance Grady (2 episodes, 2007)
Cicily Daniels ... Zelda (2 episodes, 2006)
Sal Landi ... Mr. Green (2 episodes, 2006)
Michael Edward Rose ... Edgar (2 episodes, 2006)
Rhys Coiro ... Vincent Bianchi (2 episodes, 2006)
Debi Mazar ... Leah Feldman / ... (2 episodes, 2006)
